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Joint Support (COX2TAME) 90 caps (Jarrow)

Dosage: n/a

Size: 90 Softgels

β€’ Unique Blend of Herbs for Joint Support
β€’ Helps Relieve Pain Associated with Joints
β€’ Contains EPA and DHA which Help Reduce Inflammation
β€’ Helps Improve Joint Mobility and Flexibility

COX2TAME is a synergistic blend of herbal extracts and oleoresins (full spectrum herbal extracts) known to provide natural CycloOxygenase-2 (COX-2) enzyme inhibition. COX-2 inhibition is important for healthy joint function, normal cellular development (over expression of COX-2 causes abnormal cell development) and healthy aging.

β€’ COX2TAME contains Omega 3 fatty acids known to generate prostaglandins series 3 (PGE3) and inhibit COX-2.
β€’ GLA from Borage seed oil extract enhances synthesis of prostaglandins series E1 (PGE1).
β€’ Devil’s Claw contains COX-2 inhibitors iridoid glycosides, such as harpagosides, clinically proven to improve joint motility and flexibility.
β€’ White Willow Bark is a bitter herb rich in flavonoids and salicyclic acid derivatives (salicin and salicortin) responsible for inhibiting COX-2.
β€’ Other COX2TAME Herbs / phytochemicals: Curcumin, Ginger, Quercetin, Resveratrol, Green Tea: sources of powerful phenolic antioxidants that disrupt the signaling processes that activate COX-2 gene expression.

Suggested Use: Take 1 to 3 softgels per day with water or juice, with meals, or as directed by your qualified health care consultant.

Caution: DO NOT use if under the age of 18, pregnant, lactating, trying to conceive, or if using any medication.

SUPPLEMENT FACTS
Serving Size: 3 Softgels
Servings Per Container: 30
Amount Per Serving / %DV
Fish Oil (Source of Omega 3 Fatty Acids) – 290mg / *
(Providing 122mg EPA and 7mg DHA)
GLA (Gamma Linolenic Acid) – 50mg / *
(from 210mg of Borage Seed Oil 24% extract)
Resveratrol (Polygonum cuspidatum) – 16mg / *
(Derived from 200mg Resveratrol 8% extract)
Curcurmin (Curcuma longa)(95% Curcuminoids) – 300mg / *
Ginger (Zingiber officinale)(rhizome)(5% Gingerols and Shogaols) – 250mg / *
Green Tea (camellia sinensis)(45% polyphenols) – 150mg / *
Devil's Claw (Harpagophytum procumbens)(5% iridoid glycosides) – 250mg / *
White Willow Bark (Salicis cortex)(15% salicin) – 200mg / *
Quercetin – 250mg / *
*Daily Value (DV) not established.

Other Ingredients: Soybean oil, beeswax, carob extract and Lecethin. Softgel consists of gelatin, glycerin and water.

Contains: Fish.

No wheat, no gluten, no dairy, no egg, no shellfish, no peanuts/tree nuts.

1. Buttar NS, Wang KK. The β€œaspirin” of the new millennium: cyclo- oxygenase-2 inhibitors. Mayo Clin Proc. 2000 Oct;75(10):1027-38.
2. Fung HB, Kirschenbaum HL. Selective cyclooxygenase-2 inhibitors for the treatment of arthritis. Clin Ther. 1999 Jul;21(7):1131-57.
3. Goel A, Boland CR, Chauhan DP. Specific inhibition of cyclooxy-genase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett. 2001 Oct 30;172(2):111-8.
4. Martinez J, Moreno JJ. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production. Biochem Pharmacol. 2000 Apr 1;59(7):865-70.
5. Obata T, et al. Eicosapentaenoic acid inhibits prostaglandin D2 generation by inhibiting cyclooxygenase-2 in cultured human mast cells. Clin Exp Allergy. 1999 Aug;29(8):1129-35.
6. Raisz LG. Potential impact of selective cyclooxygenase-2 inhibitors on bone metabolism in health and disease. Am J Med. 2001 Feb 19;110(3 Suppl 1):43-45.
7. Stichtenoth DO, Frolich JC. COX-2 and the kidneys. Curr Pharm Des. 2000 Nov;6(17):1737-53.
8. Surh YJ, Chun KS, et al. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: downregulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res. 2001 Sep 1;480-481:243-68.

Image and text supplied courtesy of Jarrow FORMULAS, all rights reserved.

Price: S$44.95 
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